CURRICULUM VITAE SFEIR

See All Publications Mammalian polymerase theta promotes alternative-NHEJ and suppresses recombination. Stop pulling my strings – what telomeres taught us about the DNA damage response. Associate Professor, Department of Cell Biology. The former stems from the inherent inability of the replication machinery to fully duplicate linear templates. Non-telomeric role for Rap1 in regulating metabolism and protecting against obesity.

A second area of their interest is to understand how telomere dynamics impact stem cell function and leads to tumorigenesis, using the mouse as a model organism. The linearity of chromosomes creates two major problems for eukaryotic cells: Normal human somatic cells lack the activity of telomerase and gradually loose telomeric repeats during progressive division cycles until they ultimately undergo cellular senescence. Skip to Main Content. Our lab is mainly interested in understanding the basic mechanism that leads to telomere length resetting. Opens in a new tab.

The linearity of chromosomes creates two major problems for eukaryotic cells: The linearity of chromosomes creates two major problems for eukaryotic cells: Polymerase theta is a robust terminal transferase that oscillates between three different mechanisms during end-joining.

curriculum vitae sfeir

The former stems from the inherent inability of the replication machinery to fully duplicate linear templates. Is this your profile?

TIMO NASSERI CURRICULUM VITAE

Mammalian polymerase theta promotes alternative-NHEJ and suppresses recombination. The latter refers to the propensity of linear chromosome ends to be recognized as DNA double stranded breaks.

  U OF T SGS THESIS SUBMISSION

Our lab is mainly interested in vitas the basic mechanism that leads to telomere length resetting. Normal human somatic cells lack the activity of telomerase and gradually loose telomeric repeats during progressive division cycles until they ultimately undergo cellular senescence. See All Publications Skip to Main Content.

curriculum vitae sfeir

Telomeres are replenished by telomerase, a reverse transcriptase that is active in the germ line and during early embryonic development. Areas of Research Interest and Expertise: Stop pulling my strings – what telomeres taught us about the DNA damage response. Journal of Cell Science.

Hesam Rahmanian Curriculum Vitae

Telomeres at a glance. A second area of interest to us is to understand how telomere dynamics impact stem cell function and leads to tumorigenesis, using the mouse as a model organism.

Telomeres are replenished by curriculym, a reverse transcriptase that is active in the germ line and during early embryonic development. To surmount both problems, cells use telomeres, the specific nucleoprotein complexes that are essential to ensure genomic stability and promote cellular survival. PhD from Southwestern University.

Rana Salam Curriculum Vitae – Selections Arts

Associate Professor, Department of Cell Biology. Non-telomeric role for Rap1 in regulating metabolism and protecting against obesity. A second area of their interest is to understand how telomere dynamics impact stem cell function curriculym leads to tumorigenesis, using the mouse as a model organism. Normal human somatic cells lack the activity of telomerase and gradually loose telomeric repeats during progressive division cycles until they ultimately undergo cellular senescence.

  ANALYTICAL ESSAY ON OSCAR WILDES RESQUIESCAT

The former stems from the inherent inability of the replication machinery to fully duplicate linear templates. Opens in a new tab. In particular, we rely on nuclear reprograming as a platform to identify factors that regulate telomere length.

The latter refers to the propensity of linear curricklum ends to be recognized as DNA double stranded breaks.

Victor Petrus Sfeir – Vicipaedia

Agnel Sfeir is mainly interested in understanding the basic mechanism that leads to telomere length resetting. Stressed telomeres without POT1 enhance tumorigenesis [Editorial]. To surmount both problems, cells use telomeres, the specific nucleoprotein complexes that are essential to ensure genomic stability and promote cellular sfeur.